Seventeen-year-old Greg has managed to become part of every social group at his Pittsburgh high school without having any friends, but his life changes when his mother forces him to befriend Rachel, a girl he once knew in Hebrew school who has leukemia.

Soon after moving to Noble's Green, Pennsylvania, twelve-year-old Daniel learns that his new friends have super powers that they will lose when they turn thirteen, unless he can use his brain power to protect them.

Fourteen-year-old Matt, abused by her father, has spent years being shuffled around to relatives, and has worked hard to make herself invisible, but her life changes when she moves in with Sam and Jessica Fox, a Quaker couple who quickly make her feel safe, and who Matt feels compelled to stand up for when their anti-war sentiments and peace vigils come under attack in their Pennsylvania town.

"Taylor Edwards' family might not be the closest-knit--everyone is a little too busy and overscheduled--but for the most part, they get along just fine. Then Taylor's dad gets devastating news, and her parents decide that the family will spend one last summer all together at their old lake house in the Pocono Mountains. Crammed into a place much smaller and more rustic than they are used to, they begin to get to know each other again. And Taylor discovers...

Sixteen-year-old Cordelia and her family move into the house they just inherited in Pennsylvania, a former insane asylum the locals call Hysteria Hall--unfortunately the house does not want defiant girls like Delia, so it kills her, and as she wanders the house, meeting the other ghosts and learning the dark secrets of the Hall, she realizes that she has to find a way to save her sister, parents, and perhaps herself.

Eighteen-year-old Ash wants nothing to do with senior prom, but when disaster strikes and her desperate friend, Nat, needs her help to get it back on track, Ash's involvement transforms her life.